Synthesis of functionalized 1-aminoisoquinolines through cascade three-component reaction of ortho-alkynylbenzaldoximes, 2H-azirines, and electrophiles

Authors : Reyhaneh Hosseinijei, Hossein Zahedian Tejeneki, Ali Nikbakht, Frank Rominger, Saeed Balalaie

DOI : 10.1039/d2ob00275b

Volume : 20

Issue : 15

Year : 2020

Page No : 3076-3080

An efficient strategy for the synthesis of functionalized 1-aminoisoquinoline derivatives has been developed through the reaction of o-alkynylbenzaldoximes with 2H-azirines using electrophiles.


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