Authors : Anshul Singh
DOI : 10.18231/j.jdpo.2019.066
Volume : 4
Issue : 4
Year : 2019
Page No : 327-331
Hepatoid adenocarcinoma (HAC) is a very rare malignant tumor of extrahepatic origin which is
characterized by having foci with features of both hepatocellular differentiation as well as adenomatous
differentiation. It is most commonly seen in the stomach, however, few cases of HAC originating in the
ovary, small intestine, colon, lung, uterus, pancreas, gallbladder, oesophagus and periampullary region have
also been reported. Interestingly, it morphologically and functionally resembles Hepatocellular carcinoma,
which can make the diagnosis challenging. Identification of HAC is necessary as it is associated with
a dismal prognosis. We report here a case of a metastatic hepatoid adenocarcinoma of an unknown
primary presenting in the ascending colon with both hepatoid and mucinous adenocarcinomatous areas
on morphology.
Keywords: Gastrointestinal tract, Hepatic like, Tumor.