Authors: Akash Gajendra, Tripti Vatsalya, Vikas Gupta, Vandana Pandey*, Shikha Mehrotra
Background and Aims: The study was conducted to assess & compare the effect of pretreatment with intravenous Dexmedetomidine and Magnesium sulphate on characteristics of SAB with hyperbaric bupivacaine. Materials and Methods: 80 ASA grade I and II patients (age: 18-60 years) scheduled for infraumblical surgery under spinal anesthesia were included & randomly divided into group-D (dexmedetomidine 1? gm/kg) and group-M (magnesium sulfate 50 mg/kg). patients were given prefixed doses of either intravenous dexmedetomidine or Magnesium sulfate 15 mins before SAB. Incidence of hypotension, highest level & duration of sensory & motor blockage, duration of analgesia, vasopressor requirement and incidence of sedation, nausea & vomiting were compared. Results: Highest upper level of sensory block after SAB was higher in group-D (p value < 0> Conclusion: Study suggests that Intravenous dexmedetomidine at a dose of 1?g/kg is a better adjuvant to 0.5% hyperbaric bupivacaine than MgSo at a dose of 50 mg/kg in infra-umbilical surgeries, with complications of hypotension and bradycardia occurring at acceptable incidences. Keywords: Intravenous dexmedetomidine, Magnesium sulphate, Subarachnoid block (SAB), Adjuvents, analgesia, Infraumblical surgery
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