B Jyotchna Devi

Abstract

Introduction: Quality in laboratory medicine refers to satisfaction of the needs and expectations of users or customers which can be achieved by providing a guarantee in each and every step like the whole testing process which in turn includes the physician ordering the test, pre – analytical, analytical, post – analytical phases and finally the results for interpretation. The aim of this study is to highlight human dependent errors that affects biochemical tests, through cases which we encountered in our lab. Conclusion: To prevent these errors, a symbiotic and synergistic participation should be there amongst the lab personnel and the health care team. This goal can be achieved with proper education and training of individuals involved in this process. Thus, prevention of these errors will help in better and effective patient management. Keywords: Errors, Hyperkalemia, Hypernatremia, Lipemic, Preanalytical.

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Abstract

Serum Paraoxonase is an esterase, along with Apolipoprotein A1 and Clusterin (Apolipoprotein J), PON 1 is associated with HDL. This study was done to assess the significance of serum Paraoxonase as an biomarker along with standard liver function tests in evaluating alcoholic cirrhosis. Serum Paraoxonase levels was estimated in 30 patients diagnosed with alcoholic cirrhosis and 30 healthy blood donors. Paraoxonase levels were significantly lower in cases as compared with controls (P Conclusion : Serum Paraoxonase is sensitive marker for patients with alcoholic liver disease and oxidative stress and should be included as an additional parameter along with the other parameters in liver function tests. Keywords: Alcoholic cirrhosis, Antioxidant, Paraoxonase, Liver function tests.

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