Ankush Sarwal

Abstract

Retinoblastoma amounts to be the most common intraocular childhood malignancy. More than 95% retinoblastoma are diagnosed before age five. Retinoblastoma may be sporadic or inherited. In both cases the tumor origin is biallelic mutation. Staging of retinoblastoma is based on intraocular location, extraocular & extraorbital spread, central nervous system involvement and systemic metastases. Diagnosis and management of retinoblastoma demands multidisciplinary approach, for which accurate imaging is indispensable. Concerns of the effects of radiation in retinoblastoma have led to a shift from radiation therapy to chemotherapy and locoregional treatment and magnetic resonance imaging becoming the standard imaging modality for diagnosis, staging and treatment monitoring. Keywords: Retinoblastoma, Retinoblastoma with Intracranial extension, Recurrent retinoblastoma.

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Abstract

"Crohn’s disease (CD) is a chronic and relapsing inflammatory bowel disease (IBD) that can affect the entire gastrointestinal tract. Free bowel perforation in CD is a relatively rare complication. In this report, we present a case of free colonic perforation in a patient whose final biopsy came out to be Crohn’s disease, which is a rare presentation in a patient with Crohn`s disease and we discuss this rare complication." Keyword: Crohn's disease, Colonic perforation.

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