Bela Padhiar

Abstract

Background: Acne is a common and complex and multifactorial skin disease that affects individuals of all ages. It commonly presents as Seborrhoea and formation of comedones, papules and pustules. Aim of our study is to evaluate various new chemical peeling agent for search of treatment which stand out with maximum efficacy and least side effect. Materials and Methods: A total 120 patients were included in our study. Grading of acne was done according to Pillsbury classification and divided into five Treatment groups: Group A: Azelaic peel (20% Azelaic acid peel) Group B: Black peel (8% Acetic acid peel) Group C: Kojic acid peel (12% kojic acid peel) Group D: Lactic acid peel (90% lactic acid peel) Group E: Mandelic acid peel (35% mandelic acid peel). Patients in each arm were subjected to respective chemical peels at an interval of 15 days for a total of 6 sessions. Last visit was done at 12th week. Evaluation done by dermatological examination for acne including counting the number of comedones, papules and pustules. Results: Patients with improvement at the end of 12 weeks the overall reduction rate was 60.4%, 72.4%, 24.1%, 35.2% and 50.1% with Azelaic peel, Black peel, Kojic acid peel, Lactic acid peel and Mandelic acid peel respectively. Conclusion: Our study thus concluded that the efficacy of Black peel is highest in the treatment of acne vulgaris grade I to III in Indian patients. The resolution was also observed good with Azelaic acid and Mandelic acid while response was not up to the mark by Lactic acid and Kojic acid peel. However, immediate erythema and burning sensations were more common side effects with black peel. Though the side effects observed with these peels reduced by itself, application of emollients, mild steroids and sun screeners hastened the recovery. Keywords: Azelaic acid peel, Black peel, Kojic acid peel, lactic acid peel, Mandelic acid peel

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Background: Androgenic alopecia (AGA) is a type of progressive hairloss, where there is androgen mediated conversion of susceptible terminal hairs into vellus hairs, in genetically predisposed individuals. Aims and Objectives: To compare efficacy of Topical 5% Minoxidil alone versus Topical 5% Minoxidil with Autologous Platelet Rich Plasma (PRP) therapy in patients with Androgenetic Alopecia. Materials a nd Methods: This is a Prospective study conducted in Department of Dermatology GMERS Medical College, Gandhinagar, Gujarat. A convenience sample of 62 men in the age group of 20-40 with Grade 2-5 AGA according to Hamilton- Norwood Grading were selected and was divided into 2 groups of 31 each. Presitting digital photographs and dermoscopic photos were taken. Autologous PRP was prepared using 18 ml of patients blood after double spin centrifugation and injected by Nappage technique. Results were assessed at the baseline and at the end of each sitting on the basis of change in hair density, photographic evaluation and patient’s self satisfaction. Result: Highly significant increase in hair density was achieved after 4 months of treatment. At T4 (Fourth Session of treatment) Group B showed higher hair density (42.97± 8.96) as compared to Group A (36.94 ± 11.57) which was statistically significant at P = 0.03 Conclusion: Group B showed better improvement as compared to Group A.PRP treatment has a positive therapeutic effect on male Androgenetic alopecia without major side effects. Keywords: Androgenic alopecia, Minoxidil, Platelet Rich Plasma, Randomised open label study.

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Introduction: Tattooing has been practiced for at least two thousand years. Much effort has been exerted in attempting to make tattoos brighter, more colourful and stable. In the present, it is believed that laser therapy is the best method in cosmetic terms of tattoo removal. Aims: Evaluate the efficacy and safety of Q switched ND YAG laser in tattoo removal. Materials and Methods: This was a “randomized, prospective, interventional” single centre study carried out in dermatology outpatient department of GMERS Medical College, Gandhinagar, Gujarat, a tertiary care teaching hospital in western India. Total 89 patients with tattoo of red, green, blue and black colour in scripted on different parts of their body according to inclusion and exclusion criteria were enrolled for a period of 1 year and 5 months (January 2016 -May 2017) in our study. Results: Majority of the participants (58.5%) were from 21-25 years of age group. Mean age of participants was found out to be 21.9 years. Amature tattoo 63(70.8%) were outnumbered then professional tattoo 26(29.2%). Blue-black tattoo (92.1%) was more common than red-green (7.9%) colour tattoo. Most common reason for tattooing was fashion (69.7%). More than three fourth participants (78.7%) needed 6 sittings for tattoo removal. In 13.5% participants, it was 10 sittings while in others (7.8%) it was 3-5 sittings. Conclusion: Excellent response was seen in amature tattoo group as comparison to professional tattoo group and almost all of the study participants were either satisfied or very satisfied. Only minor adverse reactions were reported after tattoo removal. Keywords: ND YAG laser, Blueblack tattoo, Red green tattoo, Amature, Professional.

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Introduction: Pediatric dermatology is an important branch of dermatology that deals with the diagnosis, treatment, and prevention of skin diseases occurring in infancy, childhood, and adolescence. Aims:The present study was conducted to find out the pattern and prevalence of various dermatosis among the paediatric age group. Materials and Methods: This is prospective, cross sectional study. A total 2456 patients were recruited in 1-14 year of age, who presented with dermatosis in dermatology clinic of GMERS medical college, Gandhinagar. The study was conducted from March 2016 to February 2017(12 Months), and diagnosis was made based on clinical examination and necessary investigation if required. Results: Males were outnumbered female in present study with ratio of 1.45:1. The majority of patients were in the age group of >6-14 year (44.09%). Infections and infestations were most common constituting 65.19% followed by eczema and dermatitis group of disorder constituting 12.02% (n=324). Appendageal disorder constitutes 6.42% (n=173) followed by cutaneous vascular response (4.27%), nutritional dermatosis (2.67%), pigmentary disorder (2.15%), keratinization disorder (2.0%) and papulosquamous disorder (1.89%). Least common disorder include nevi, genodermatoses, collagen vascular disorder and vesiculobullous diorde. Conclusion: This study helps us to know the prevalence of skin diseases in pediatric age group and thus we can take adequate measures for their prevention and treatment in this region. Keywords: Paediatric, Dermtoses, Infections and Infestations.

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