Authors: Shirish S Chandanwale, Piyusha Naragude, Madhuri Singh, Gore Charusheela, Aishwarya Desai, Sadbhawana
Introduction: Kidneys are involved in variety of pathological processes. Renal diseases are an important cause of morbidity worldwide. Chronic pyelonephritis and its variants still continue to be the leading cause of nephrectomies in developing country like India. In some developed countries, neoplastic lesion is the commonest indication for nephrectomy. Aim: The study is carried out to study the frequency of various neoplastic and non-neoplastic lesions in nephrectomy specimens and to study histomorphological features in a teaching hospital. Materials and Methods: The t otal of 50 nephrectomy cases were studied. Detailed clinical finding were collected from case sheets. Detailed gross findings and histomorphological features were studied. Results: Out of 50 lesions 35 were non neoplastic and 15 were neoplastic. Out of 35 nephrectomy lesions, 32 cases were of chronic pyelonephritis and males (n=18) were commonly affected than female (n=14). Out of 15 neoplastic lesions majority(n=12) were renal cell carcinoma and most commonly (n=12) involved males. Conclusion: In developing country like India pyelonephritis is the commonest cause of nephrectomy. Better treatment modalities of inflammatory lesions of kidney in the develop ing countries will reduce the rate of nephrectomies. Keywords: Kidney, Carcinoma, Chronic, Pyelonephritis.
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