Sheetal B Ghivari

Abstract

Context: The success of endodontic treatment lies in adequate debridement of the root canal. There are various microorganisms responsible for the failure of root canal treatment, one among them is . Sodium hypochlorite is considered as the gold standard. Since it has various disadvantages newer irrigants like Curcumin and Chitosan nanoparticles have been tried. Aim : The aim of this study was to evaluate the preliminary anti-microbial efficacy of Curcumin and Chitosan nanoparticles with and without photoactivation against Materials and Methods: The antimicrobial activity of Curcumin, Chitosan nanoparticles with and without Photoactivation, Saline and Sodium hypochlorite was assessed. MIC was done with serial dilution method, incubated for 48-72 hours and?observed for turbidity.MBC was done from the MIC dilutions tubes, first 3 tubes were plated, incubated for 24 hrs and the colony was counted. ?For Time kill assay broth with the compound was mixed, plated and inoculated at 1hr, 2hrs and 4hrsinterval and colony count was noted. Statistical analysis: Results were tabulated and statistical analysis was done using Analysis of Variance (ANOVA) and Tukey multiple comparison test. Results: Photoactivated Curcumin has shown the best antimicrobial results as compared to Curcumin, Chitosan nanoparticles (photoactivated and nonphotoactivated) and 3% Sodium hypochlorite. Conclusion: Curcumin with and without photo activation and Chitosan nanoparticles can be considered as an alternate endodontic irrigants against sodium hypochlorite.   Keywords: Cytotoxicity, Herbal intracanal medicament, Calcium hydroxide, Ganoderma Lucidum, Psidium Gujava, Modified Triple antibiotic paste

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Abstract

Endodontic biofilm exist in the form of aggregates and a coaggregate attached by glycocalyx membrane is considered as primary etiology for endodontic infections. The primary goal of endodontic treatment is to eliminate the biofilm from root canal walls which is responsible for endodontic infection. Biofilm formed by endodontic pathogens is resistant to antimicrobial disinfection procedures there fore new approaches for elimination of biofilm have been introduced such as lasers, photo activated disinfection and nanoparticles. Keywords: Biofilm, Anti biofilm, Root canal irrigation, Intracanal medicaments.

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Abstract

Oral health is closely related to general health which needs special attention in elderly patients. In order to provide health care to elderly patients understanding their mental, physical and psychosocial needs is very important. In due course of old age many physiologic changes takes place in many organs of the body including teeth. Considering the oral changes the treatment strategies for elderly patients need to be modified. A thorough counseling is required to bring the change in their thought process that tooth loss is part of ageing process. Keywords: Elderly, Oral health, Tooth loss.

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