Abilash Sasidharannair Chandrakumari

Abstract

Kikuchi disease also known as histiocytic necrotizing lymphadenitis, is a benign and self-limited disease mainly affecting women. Clinically and histologically, the disease is mistaken for lymphoma or systemic lupus erythematosus. It merits recognition and importance since it almost always runs a benign course and resolves in several weeks to months. Complications are rare and the prognosis is excellent. We report a case of Kikuchi Disease in a male patient with a deviant presentation. Keywords: Kikuchi disease, Histiocytic necrotizing lymphadenitis, Benign, Selflimiting.

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Abstract

Introduction: Ovarian cysts and tumors are the major health problem in women. Ovarian Cysts are the most prevalent pelvic mass and often associated with function disorders of menstruation which are mostly improved spontaneously. In some cases which are the result of cyst rupture, torsion or bleeding in to the cyst, laparotomy may be needed. Aim: The aim of this study is to highlight the histopathological study of ovarian cysts in rural area. Materials and Methods: Hematoxylin and eosin stained slides of ovarian biopsies for 4 years were archived, scrutinized, and studied. Request forms were analyzed for clinical biodata and diagnosis, and data were analyzed with Statistical Package for Social Sciences (SPSS) version 21. Results: Total number of 197 ovarian biopsies were reviewed. Out of which, 149 (75.6%) of nonneoplastic (functional cysts) lesions, 37 (18.7%) benign neoplastic lesions and 11 (5.5%) malignant tumors. Corpus luteal cyst was the most commonly encountered ovarian functional cyst constituting 63 cases (42.2%). This was followed by follicular cyst 42 cases (28.1%). The peaks age incidence for non-neoplastic is 3rd decade. Conclusion: Functional ovarian cysts were the most commonly encountered ovarian lesions in our rural area. The most common variety of functional cyst was corpus luteal cyst and follicular cyst with majority occurring in the reproductive age groups. Keywords: Ovarian lesions, Functional cysts, Corpus luteal cysts, Follicular cyst.

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Introduction: Gallstones are the commonest biliary pathology, the incidence ranging from 10% to 20% of the world population. Over 95% of biliary tract disease is attributable to cholelithiasis. Gallbladder stones are known to roduce histopathological changes in the gallbladder. Aim: To study the spectrum of gallbladder pathology in cholecystectomy specimens. Materials and Methods: The study was conducted from January 2011 to December 2014 in the department of pathology, tertiary care centre. A total of 197 cases of cholecystectomy specimens were stained using hematoxylin and eosin and evaluated. Results: Gallstones and associated diseases were more common in women within 4th to 5th decade, with a aximum number of patients being 41 to 50 years. Histopathologically the most common diagnosis was chronic calculous cholecystitis amounting to 122 cases. Female preponderance was observed in all gallstone diseases. Gallstones were present in 126 cases and significantly associated with various lesions. Pigment stones were most common. The present study carried out in our institution showed gallbladder malignancy was uncommon and was seen only in two cases. Conclusion: Almost all of the gallbladder lesions are inflammatory in origin, of which the most common disease being chronic calculous cholecystitis presenting with abdominal pain. Pigmented gall stones were found to be the most common etiology of chronic cholecystitis. Keywords: Gall stones, Cholecystitis, Chronic Inflammation.

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