Poonam Lalla

Abstract

Diabetic Nephropathy in the long run leads to end Stage Renal Disease (ESRD). Serum Creatinine and Serum Urea are recognised as ideal markers to co-relate the progression of diabetic nephropathy. Diabetic Nephropathy is clinically diagnosed with decrease in Glomerular function rate (GFR), probability of hypertension, cardiovascular diseases and morbidity or mortality caused due to it. The early detection of an imbalance in the level of Urea and Creatinine levels can assist in the diagnosis and prevention of Diabetic Renal diseases and its progression. In this study, the period of the commencement of Diabetes and its severity is intensely correlated with an abnormal level of Urea but not so with that of Creatinine. While Creatinine is regarded as greater sensitive index of kidney function than Urea and hence this justifies as the requirement for a perfect filtration marker. Keywords: Diabetic nephropathy, ESRD-End stage renal disease, Serum urea, Serum Creatinine, Diabetes, GFR-Glomerular function rate, Type 2 diabetes, Diabetes mellitus Transasia.

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Abstract

CRP is one of the reliable diagnostics marker used in diagnosis of Neonatal Sepsis that has been widely available, most studied and preferred over the newly emerging infection markers. In this study, we have studies that even CRP assay has proven to be less time consuming and effective analyzing samples of neonates who are already on antibiotics treatment. In our study 40 neonates were proved to have neonatal sepsis which was based on signs and symptoms shown by patient. The other studies have revealed, CRP biochemistry assay have high sensitivity and specificity as compare to HSS for diagnosis of NS; we also got 100% sensitivity and specificity for CRP testing. Hence we concluded that CRP is a good diagnostic marker for the infection in neonates at the time of initial assessment. In our study we used quantitative assay for CRP estimation which less time consuming and effective in analyzing samples of neonates who are already on antibiotics treatment. Keywords: CRP, C-reactive proteins, Neonatal Sepsis, Transasia, Erba, Pathology, Blood Culture, HSS, Neonatal Septicemia, Dr Godbole Laboratory, Pune, Signs of neonatal sepsis.

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Abstract

Iron Deficiency Anemia in pregnancy is prevalent in developing countries which can be reduced by oral iron supplement. Iron Deficiency Anemia is also the root cause for preterm birth, low birth weight and poor mental and physical development of baby. This may link to development of high blood pressure in the adult life. Hence, it is very important to diagnose the Iron Deficiency Anemia in early stage of pregnancy. Hemoglobin and serum ferritin both are apt markers for Iron Deficiency Anemia diagnosis. However, serum ferritin is considered to be the best marker over hemoglobin as hemoglobin is a delayed marker and may fail to reflect tissue iron status. In current study we have analyzed the primigravida and multigravida pregnant women with a control group to check the serum ferritin level and evaluate the Iron Deficiency Anemia status.   Keywords: Ferritin, Iron deficiency Anemia, Pregnancy, Hemoglobin level, Anemia.

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