Authors: Poonam Agrawal, Shinky Mehta, Niket Verma
Introduction: Vitamin D deficiency (VDD) is a global health concern. Previous studies have shown significant deficiency of vitamin D in hypothyroid subjects compared to euthyroid subjects with higher deficiency in the female population compared to males. Materials and Methods: A total of 70 adult females aged 41-65 years were enrolled in the study after obtaining their informed written consent. They were categorized into 2 groups consisting 35 Hypothyroid cases and 35 Euthyroid controls respectively. Serum vitamin D, TSH, fT3 and fT4 levels were assessed by chemiluminescent immunoassay (CLIA). VDD was designated at levels lower than 20 ng /ml and Vitamin D insufficiency (VDI) at level between 20 ng /ml - 30 ng /ml. Levels > 30 ng /ml were stated as vitamin D sufficiency state. Level Results: The study shows significantly reduced levels of Vitamin D in hypothyroid female subjects compared to age and gender matched euthyroid controls. Majority of hypothyroid subjects and euthyroid controls were falling in VDD range rather than VDI range. We also observe that hypothyroid subjects were more in VDD category as compared to euthyroid subjects. Keywords: Vitamin D Deficiency, Hypothyroidism, Thyroxine, Thyrotropin.
Open full article page