Nimish Vador

Abstract

Psoriasis is an autoimmune disorder. It is characterized by chronic inflammatory condition of skin. It leads to thick, scaly plaques on skin . Current medication involves symptomatic treatment by the various moisturizers, however, the effects do not last long and recurrence occurs. Based on several ancient text a combination of herbs was formulated and named as Skimune tablet and Gel. Preclinical safety was conducted which was found to be safe for the dose above 5000 mg/kg of body weight. The beneficial effects of Skimune Tablet and Gel was clinically evaluated on patients with mild to moderate psoriasis. The Dermatology Life Quality Index (DLQI) and Psoriasis area & severity index (PASI) score was evaluated to understand the effects of tablet and Gel. Skimune tablet was found to be safe upto 5000mg/kg of body weight in animals and was well tolerated in patients too. Skimune Tablet and Gel showed significant improvement (P Keywords: Skimune, Psoriasis, Ayurveda, Inflammation, Chronic.

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Abstract

Hyperacidity (Amlapitta) is one of the most common disorder. It is observed by excess production of gastric acid in stomach. It is generally imbalance between offensive parameters like gastric acid and defensive factors like mucin bicarbonate secretions. Over the counter products aim at neutralizing gastric acid rather than the root cause. Ayurvedic preparations has an solution to amlapitta. It not only neutralizes acid secreted but also improves defensive properties of stomach. Once such combination is Ulsant tablets. Acid neutralizing capacity and buffering capacity was conducted in vitro. The aim of the present study was to find out safety and efficacy of Ulsant tablet. In present study total 35 patients were taken. Patients were advised with Ulsant tablet 2 tab twice a day for 45 days. Results shown significant positive results with respect to acid neutralizing capacity, buffering capacity and clinical symptoms. Keywords: Hyperacidity, Ulcer, Ayurveda, Ulsant, Natural.

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Abstract

Traditional system of medicines has been in use since ages throughout the world. Ayurvedic granthokt extracts have been in use to treat many disorders which are either non-communicable or lifestyle oriented or due to stress. Rheumatoid arthritis is one of the autoimmune disorder which might arise due to faulty metabolism of body or stress. It is a chronic inflammatory disorder which results in severe pain, discomfort and sometimes disability in the patients. Modern medicines aims to reduce pain but the root cause remains unattended. Hence the main objective was to assess the in vitro Antioxidant and Anti-inflammatory activity of the Ayurvedic formulation Maharasnadi kwath extract and Stifain tablet. The Antioxidant properties of the Maharasnadi kwath and Stifain tablet were evaluated by 2, 2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging assay. Anti-inflammatory activity was estimated by inhibition of protein denaturation method. The aqueous extract of Maharasnadi and Stifain tablet showed good anti-inflammatory activities and potent antioxidant capacity.   Keywords: Antioxidant, Anti-inflammatory activity, Albumin denaturation, Maharasnadi kwath, Stifain tablet, Nervous system.

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