Harshitha Arun Pardhe

Abstract

Depression is an affective mental disorder characterized by extreme exaggeration and mood disturbances. The aggregate of genetic, environmental and psychological factors may lead to depression leading to decreased brain levels of monoamines such as noradrenalin, dopamine and serotonin. A massive wide variety of synthetic drugs are available for depression furthermore the side effects like dry mouth, nausea, gastrointestinal problem or respiratory problems, drowsiness, anxiety and cardiac arrhythmias are major restrictions in their application. Therefore the drug which restores the reduced level of monoamines in brain and might be beneficial remedy for depression. Researchers are presently seeking for more specific alternative antidepressants from natural source with high safety and lower costs. The purpose of this review is to enlist those plants having antidepressant activity. Keywords: Antidepressants, Forced Swim test, Tail Suspension test Immobility.

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Abstract

Pulmonary embolism (PE) is characterized as pulmonary artery obstruction caused by a thrombotic embolus the usual clinical presence of acute PE involves a patient with a sudden onset of dyspnea and pleuritic chest pain at breathing, while blood coughing (hemoptysis), signs of deep vein thrombosis (DVT) and even collapse are less prevalent. PE is classified as PE which is massive, sub-massive and low risk. PE is a significant cause of morbidity and mortality among the patients who are hospitalized. When venous clot is dislodged from the place where it was actually formed, the clot then proceeds towards a vessel of pulmonary circulation leading to pulmonary embolism. Many factors affect pulmonary embolism such as prolonged immobility, advanced age, postoperative time, post-infarction period, heart failure, obesity, pregnancy, etc. Treatment mainly involves anti- coagulants. This brief review summarizes the pathophysiology, risk factors and treatment, management and supportive measures involved in Pulmonary embolism. Keywords: Pulmonary Embolism, Deep vein thrombosis, Bronchospasm, Thromboembolism.

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