Sonia Bhargav

Abstract

Objective: The aim of this study was to assess the efficacy of commercially available sterile lid wipes in reducing the incidence of MGD and dry eye after cataract surgery. Materials and Methods: In this prospective clinical study 40 patients undergoing uneventful cataract surgery were included. They were divided randomly into 2 groups of 20 patients each. The control group was prescribed standard postoperative regimen consisting of topical steroid, antibiotic and NSAID. The study group was prescribed in addition to the above topical regimen, sterile lid wipes for cleaning of lid margin and lashes. The signs and symptoms of all patients were assessed and scoring was done based on severity grading of a structured symptom based Standard Patient Evaluation of Eye Dryness (SPEED) questionnaire, corneal staining, meibum expressibility and meibum quality at preoperative and at postoperative 3 weeks and 6 weeks. The data obtained was analysed statistically. Results: The SPEED questionnaire, corneal staining, meibum expressibility and meibum quality mean scores worsened statistically significantly in the control group as compared to the study group (p In control group, the mean score of all the parameters were statistically significantly worsened at all follow up visits. (p Conclusion: Maintaining lid hygiene with lid wipes in post cataract surgery period is effective in prevention of MGD and dry eye. Keywords: Dry eye, Meibomian gland dysfunction (MGD), Lid wipes, Post cataract surgery.

View Article

Abstract

Introduction: Postoperative dry eye and meibomian gland dysfunction (MGD) is common cause of morbidity. Its cause is still elusive and probably multifactorial. Various studies in the past have thrown some light on its mechanism but still we are not able to prevent its occurrence. Till date no study has analyzed the role of topical steroid as one of the factors influencing postoperative MGD and dry eye. Purpose: The aim of this study was to compare the symptoms and signs of MGD and dry eye in postcataract surgery patients treated with topical dexamethasone-moxifloxacin versus topical prednisolonemoxifloxacin combination eye drops. Materials and Methods: Seventy eyes of seventy patients of senile cataract who had no dry eye signs preoperatively, and had undergone uncomplicated phacoemulsification surgery were selected. The patients were divided randomly into two study groups – Group 1 patients were started on dexamethasone sodium phosphate -moxifloxacin hydrochloride and Group 2 patients were started on prednisolone acetate – moxifloxacin hydrochloride combination eye drops postoperatively in a tapering dose for 6 weeks. The data collected by scoring of clinical dry eye signs (corneal staining, TBUT, Schirmer test I and meibomian gland dysfunction assessed by meibum expressibility and meibum quality score) and symptoms scoring by SPEED II questionnaire. The study was done in both the groups preoperatively and at 1 week, 4 weeks and 8 weeks postoperatively. Both the groups were compared using independent paired t- test and Mann – Whitney test. Results: The mean values of SPEED II, TBUT, corneal staining, meibomian gland expressibility, meibum quality were statistically significantly higher in all followup visits (at 1week, 4 weeks, and 8 weeks) in group 2 as compared to group 1.(p

View Article