Authors: Varsha Patel G.B, Sujatha G.P, Sangeeth Siddabasappa, Ashok L
An important group of lesions in the oral cavity are autoimmune mucocutaneous diseases. The diagnosis of pemphigus vulgaris is made using clinical, histologic, and immunologic criteria, with older patients being the most frequent victims. Pemphigus vulgaris is an autoimmune blistering disorder that typically affects the oral mucosa. Autoantibodies against the desmoglein component of keratinocytes are the hallmark of this disease. Clinically, it appears as vesicles, bullae, or desquamative gingivitis, and histological analysis reveals that acantholysis is present. The diagnosis is typically confirmed by immunofluorescent evidence of IgG antibodies against desmoglein. Pemphigus vulgaris must be considered in the differential diagnosis of oral vesiculo-bullous lesions due to its clinical similarities to other oral illnesses. The physician can provide appropriate care by using diagnostic and therapeutic methods with sufficient understanding. This paper presents a case report of pemphigus vulgaris affecting oral cavity. This paper presents a case report of pemphigus vulgaris affecting oral cavity. Keywords: Autoimmune disorders, Oral mucosa, Pemphigus vulgaris
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