Suresh Mandrekar

Abstract

Background: Renal cell carcinoma (RCC) accounts for 80-85% of malignant kidney tumors. However incidence of RCC is less in Asian Countries including India and data available from Indian studies is scarce. Outcome of RCC depends on the morphological type and hence accurate classification is essential. Aims and Objectives: The objective of the present study was to assess the profile of patients of RCC in respect to age distribution, Sex distribution, laterality of the tumor, location within the kidney and Pathological tumor stage and compare our results with available literature from India and other countries. Material and Methods: The study is a retrospective study, which was conducted over a three and half year period from January 2016 to June 2019 at Goa Medical College, Bambolim Goa. A total of 60 cases of RCC diagnosed over this period were included in the study. Patient details were obtained from the Histopathology requisition forms from the records of Pathology department. The data was collected, analysed and compared with other similar studies. Histopathological examination of the specimens was conducted using standard processing technique and taking 5 micron sections and staining by Hematoxylin and Eosin technique. Results: A total of 60 cases of RCC were diagnosed over 3and 12 year period with Clear Cell Carcinoma 38(63.3%) cases being the commonest histopathological type. The tumor was more commonly seen in males with a M:F ratio of 3.6:1. The age ranged from 25 to 78 years with a median of 56.5 years which is decade earlier as compared to Western data. The tumor size(Pathological stage pT) in this study was lower with 24 cases(40%) being diagnosed in pTa stage and 22cases(36.7%) treated with nephron sparing surgery which is a much higher figure as compared to other Indian studies. Keywords: Renal cell carcinoma, Clear cell, Chromophobe, Multilocular cystic, Papillary.

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Abstract

Introduction: Eyelids are affected by a variety of benign and malignant conditions. A clinical diagnosis is not always correct and hence a histo-pathological study of the lesions is necessary to arrive at correct diagnosis. Aims and Objectives: To study the prevalence of various eyelid lesions at a teaching hospital and to compare the same with other studies. Materials and Methods: The study was conducted over a seven year period from January 2009 to December 2015 at Goa Medical College, Bambolim Goa. A total of 100 patients who presented to the Ophthalmology and Plastic surgery department with eyelid lesions and who were operated were included. Histopathological examination of the excised specimens was conducted using standard processing technique and taking 5 micron sections and staining by Hematoxylin and Eosin technique. Results: A total of 100 lesions were studied, of which 50(50%) were non-neoplastic and 50(50%) were neoplastic which included 41(41%) benign tumors and 9(9%) malignant tumors. The age group ranged from 2 to 85 years with the youngest patients (2 patients who were 2yrs old) presenting with pyogenic granuloma and a dermoid cyst of the eyelid respectively and the oldest was a 85 year old female with intradermal melanocytic naevus of Left upper eyelid. Keywords: Benign, Eyelid, Lesions, Malignant.

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