Muktpal Marotrao Bhalerao

Abstract

Background: Depression is caused as a multifactorial psychiatric disorder and the reasons associated are genes, environmental, psychological, and biological factors. There are several molecular changes in the pathogenesis of depression. Antioxidants in the body like catalase was found to be deranged in patients suffering from depression. Materials and Methods: The present observational cases-control study was carried out in the Physiology Department of Rural Medical College Loni in collaboration with Psychiatry department. Total 183 subjects recruited for study. Out of total subjects 83 patients were diagnosed with depression and 100 were normal individuals without any psychiatric disorder. A non-probabilistic international sampling method was adopted for the selection of subjects. Results: Significant decrease in serum catalase was observed in patient suffering from depression as compared to normal healthy individuals (p value < 0> Conclusion: The present study finds decreased serum catalase levels in patient suffering from depression as compared to the normal healthy controls. Keywords: Antioxidant, Catalase, Depression.

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Abstract

Background: According to the World Health Organization (WHO) in pregnancy hemoglobin (Hb) less than 11gm/dL refers to be anemia. Anemia is the most common nutritional deficiency affecting the pregnant women. In India prevalence of anemia in pregnant woman is about 65% to 75%. Anemia during pregnancy causes negative and harmful effects on mother as well as on child. Anemia increases the risk of maternal and perinatal mortality. India had the highest prevalence of anemia in pregnancy. The Highest number of anemic pregnant women in the world are in India. So the present study was planned with aim to study the anemia in pregnant women. Materials and Methods: The present case-control study was carried out in Department of Physiology at Rural Medical College Loni in Ahmednagar district of Maharashtra. The study was approved by Institutional Ethical Committee. Total 644 subjects were recruited for the study. 161 non-pregnant women were taken as control and 483 pregnant women were taken as the cases. Hemoglobin measurements of the pregnant woman was done by Sahali’s method. Hb concentration of Results: The prevalence of anemia in pregnant and non-pregnant women were 62.93% and 82.60% respectively. Conclusion: Pregnant as well as non-pregnant women in India are at high risk of developing anemia. The various national programmes aimed at prevention of anemia reduced the prevalence as well as severity of anemia during pregnancy.   Keywords: Anemia, Hemoglobin, Pregnancy.

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