Mohammad Ali R Patel

Abstract

20 patients were diagnosed with OSMF Stage III/IV were included in this comparative study. Surgical intervention was done followed by reconstruction of the raw denuded area; Bilateral (B/L) Nasolabial Flap and B/L Buccal fat pad flap. The use of either flap was subject to patient consent. Interincisal mouth opening and Complications associated with material were the study parameters. In conclusion, Both Nasolabial flap and Buccal pad fat are good options for reconstruction of the defect and we found no statistically significant difference between the two modalities at the end of 6 months post-operative follow up. We conclude Buccal fat pad and Nasolabial flap are both viable reconstruction method in surgical treatment of late stage OSMF. Keywords: OSMF, NLF, BFP, Submucous fibrosis, Buccal fat pad, Nasolabial flap.

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Abstract

Aims and Objectives: To evaluate and correlate the salivary and serum lipid profile in healthy individuals, tobacco chewers and smokers. Also, to compare the salivary lipid profile within each group statistically. Materials and Methods: A total of 60 samples were taken, 20 in each group. Fasting blood and unstimulated saliva sample collected and the lipid analysis (Total Cholesterol - TCHL, Triglycerides - TGL, High density lipid cholesterol - HDL, Low density lipid cholesterol - LDL, very low-density lipid cholesterol - VLDL) was done on an autoanalyzer based on spectrophotometric principle. Statistical analysis: Data are evaluated and statistical analysis was done using unpaired student “t” test and Karl Pearson’s correlation. Results: A moderate correlation was found between salivary and serum lipid profile of the study group and control group with exception to LDL. Low lipid profile was observed in the study group in comparison with control group. Conclusion: Saliva can be used as a non-invasive diagnostic tool for assessing lipid profile, however diagnostic value of saliva has to be determined in terms of sensitivity, specificity and reproducibility in larger samples and different disease setting. Keywords: Tobacco, Saliva, Serum, Lipids.

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