Authors: Rinkal R. Aware, Hemant J. Pagar, Ganesh D. Barkade, Shweta Dhawane
In the present study we have selected antioxidants agents like Pioglitazone and Ascorbic acid were subjected for anti-cataract activity by in vitro glucose induced cataract model. In the procedure, goat lenses was incubated along with the aqueous humor solution containing 55mM glucose with Enalpril as a standard compound and Pioglitazone with varied concentration for the time interval of 72 hours at room temperature. There was a formation of blur layer on the goat eyeball occurs after 10-12 hours and this process complete after 72 hours. The cataract inducing lenses showing higher level of Na, MDA (P Keywords: Anticataract, Antioxidants, Enalpril, Free radicals, In vitro, Pioglitazone
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