Samagani Akshay

Abstract

Subcutaneous fat necrosis of newborn is a rare cutaneous disorder affecting neonates. It usually presents as subcutaneous nodules or plaques, within the first few weeks of life, following an eventful delivery. It is characterized by hypercalcemia, which may present with lethargy, irritability, hypotonia and dehydration, mimicking sepsis. Histopathology is proven to be the gold standard in diagnosis with characteristic lobular panniculitis, mixed inflammatory cell infiltrate and radially arranged crystals. This needs to be differentiated from other causes of lobular panniculitis, as early diagnosis and treatment to prevent long-term complications are advocated. Education of parents regarding the disease and danger signs of hypercalcemia and weekly monitoring of serum calcium is recommended. Treatment based on rehydration, dietary vitamin D and calcium restriction, Furosemide and prednisolone are considered.We have discussed a case of subcutaneous fat necrosis, in an 8-week-old male baby. Key Messages: Subcutaneous fat necrosis is an important differential in neonates presenting with palpable subcutaneous nodules, along with sclerema neonatorum. Severe complications like hypercalcemia should be detected early and managed aggressively to prevent morbidities and mortalities associated with it. Symptomatic management, use of calcium lowering drugs and regular monitoring of calcium levels are recommended. Keywords: subcutaneous fat necrosis of newborn, perinatal asphyxia, hypercalcemia, lobular panniculitis, neonatal sepsis

Open full article page

Abstract

Eruptive cutaneous collagenoma is a non-familial connective tissue nevi of unknown etiology presented with an abrupt onset. To date, the literatures on eruptive cutaneous collagenoma are extremely rare in India. Herein, we report a rare case of eruptive collagenoma in a 26 year old young male with epilepsy and mental retardation, who presented with multiple asymptomatic papules and nodules over the chest and abdomen with no systemic involvement. There was no positive family history or history of consanguineous marriage, and diagnosis was confirmed histologically. We report this case due to paucity in Indian literature.   Keywords: Eruptive collagenoma, Masson's trichrome stain, Von­gieson stain

Open full article page

Open full article page