Rakhi V Jagdale

Abstract

Cutaneous meningiomas (CM) are rare variants of meningiomas which are further classified into three subtypes. Type I CM (TICM) or Rudimentary meningocele (RM) is an uncommon developmental anomaly in which meningothelial elements are displaced into the skin and soft tissue. We present a case of 11 year boy with an upper back swelling since early childhood. His MRI spine showed a lesion at T4-T7 level with a fistulous tract connecting it to dural sac. Histopathology revealed clusters of oval to spindle cells arranged in whorls amidst collagen bundles and psammoma bodies. On immunohistochemistry these cells expressed EMA and Vimentin. A diagnosis of TICM was rendered based on these characteristic clinico-radiological & histopathological features. TICM pose a diagnostic challenge clinically and histopathologically and have an excellent prognosis. This is the 4 Indian case of RM and the 1 case of RM to be located in the spine in the Indian literature.   Keywords: Cutaneous meningioma, Rudimentary meningocele, Thoracic, Type I

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Abstract

Ewing sarcoma/Primitive Neuroectodermal Tumor (ES/PNET) is a malignant small round blue cell tumor of neuroectodermal origin that affects bones and soft tissue in children and young adults. ES/PNET is very uncommon in parenchymal organs. We report a case of primary adrenal PNET in a young female having pregnancy induced persistent hypertension. She underwent right adrenalectomy for a large adrenal mass. On histopathology, it was typical malignant round cell tumor (MRCT). Immunohistochemistry confirmed the diagnosis of ES/PNET with expression of CD99, FLI-1 and NKX2.2. Until now, only 38 cases of primary adrenal ES/PNET have been reported in the English literature with just 5 cases from India. Adrenal ES/PNET can be mistaken with other MRCTs like Non-Hodgkin lymphoma and neuroblastoma. Since the biology, treatment and prognosis of these tumors is entirely different, we emphasize that pathologists must be aware of this possibility and try to differentiate them using ancillary techniques.   Keywords: Ewing sarcoma, Primitive neuroectodermal tumor, Adrenal gland.

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Abstract

Ectopic prostatic polyps are uncommon lesions, sometimes found in the lower urinary tract, particularly the posterior urethra. Ectopic prostatic tissue in the bladder is very uncommon. Until now, only 43 cases of this lesion have been reported in the English literature. Clinically and endoscopically these lesions are often mistaken for malignancy. We report a case of ectopic prostatic tissue at the bladder neck in a young male. Histopathology and immunohistochemistry confirmed the prostatic nature of the tissue. Since the entity is benign and unlikely to recur, we emphasize that urologists and pathologists need to be familiar with this to avoid misdiagnosis and unnecessary overtreatment. Keywords: Ectopic prostate tissue, Prostate-type polyp, Urinary bladder, Ectopic.

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