Manu Sharma

Abstract

Purpose: To study the incidence and risk factors of Retinopathy of prematurity in extremely low birth weight babies in a tertiary neonatal care unit in northern India. Materials and Methods: A prospective cohort study of all neonates born during January 1, 2015 to December 31, 2015, with birth weight less than 1000 grams. Demographic details, risk factors and incidence of ROP were studied. Results: Sixty babies were enrolled for the study with mean birth weight of 892.983±112.933 (560 to 1000) grams and mean gestation age of 29.47±2.258 (25-35) weeks. The incidence of ROP in this cohort was 50% (30 infants), out of which 23% (7 infants) required treatment (laser photocoagulation). The statistical analysis of risk factors on univariate analysis revealed a significant association for oxygen exposure, apnoea, surfactant use, anaemia, blood transfusion, intraventricular haemorrhage, sepsis and antibiotic use. On multivariate logistic regression analysis anemia and oxygen exposure > week were found to be independent risk factors for development of ROP. Conclusion: The incidence of ROP was although high in this exclusive cohort of babies born 1 week were found to be independent risk factors for development of ROP in this cohort.   Keywords: Retinopathy of prematurity, Extremely low birth weight, Incidence, Risk factors.

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Abstract

Phacolytic glaucoma is one of the varieties of various lens induced glaucoma, also known as lens protein glaucoma is a sequelae of hypermature cataract. In our case 60 years old male presented with lid edema, pain, redness, loss of vision of right eye with exudates or fluffy deposits in the anterior chamber mimicking endophthalmitis. Endophthalmitis is infection of eye involv ing aqueous and vitreous humors with exudates in vitreous cavity. Here we report a cytology proven case of lens induced glaucoma managed with phacoemulsification and intraocular lens implantation followed by good visual outcome. This case highlights the importance of right and early diagnosis. Keywords: Phacolytic glaucoma, Cataract, Endophthalmitis.

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