Narinder Singh

Dengue fever is a mosquito-borne viral illness that is quickly spreading over the globe, with significant death and morbidity rates. Dengue fever is an acute viral infection transmitted by Aedes mosquitos and caused by an RNA virus from the Flaviviridae family. The symptoms might vary from asymptomatic fever to life-threatening complications including hemorrhagic fever and shock. Although dengue virus infections are normally self-limiting, the disease has become a public health concern in tropical and subtropical countries. Dengue fever is a major public health concern owing to its rapid worldwide spread, and its burdens are now unmet due to a lack of accurate therapy and a simple diagnostic approach for the early stages of illness. Keywords: Dengue fever, Aedes (Ae), Clinical symptoms, Pathogenesis, Laboratory Diagnosis, Treatment

Liver is the primary site of digestion for drugs and different exogenous mixes. As most medications are taken orally the liver is the entrance to the tissues for such mixes following ingestion from the gastrointestinal tract. The biggest organ in the body is being advanced to keep up the body’s inward milieu and furthermore shield itself from the difficulties it faces during its working. It is a fundamental organ having different capacities. It assumes a significant job in the digestion, combination and capacity yet additionally in the detoxification of numerous endogenous and exogenous mixes and changing them over to less harmful substances for excretion. Hepatotoxicity suggests substance driven liver harm. Medication induced liver injury is a reason for intense and constant liver sickness. The liver assumes a focal part in changing and clearing synthetic compounds and is helpless to the harmfulness from these specialists. Other chemicals or natural chemicals agents (e.g., microcystins) and herbal remediescan also induce hepatotoxicity. Keywords: Drug induced Liver Injury, Mechanism, Types, Diseases & its symptom, Therapeutic agents.

Solubility is a process of solute in solvent to give a homogenous framework which is the significant considerations to accomplish wanted concentration of drug in the systemic circulation for wanted pharmacological reaction. The bioavailability issue can be because of inadequate Solubility of permeability. Most mixes solutions are facing the solubility issues. Subsequently, with the progression of synthetic science, the need for improvement of drug innovations is likewise expanding. The mechanisms solute solvent interaction expresses homogeneous liquid phases comprising of solute and solvent in factor proportions. The choice of solubility improving strategy relies upon drug property, site of retention, and required measurement structure attribute. Keywords: Solubility, Solubility expressions, BCS classification, Factors, Mechanisms, Biological principle.

In the battle against COVID-19 Pharmacist (Pharmacy officer) have been fundamental to keep the pandemic under control, however acknowledgment of individual callings' endeavors have been conflicting at all levels. Pharmacist Play more valuable role in different fields for prevention the COVID 19 Prevention such as frontline pharmacists, Community pharmacists, Hospital pharmacists, Clinical pharmacists. Community pharmacists are the most open medical services experts. Which are demonstrated during the pandemic as they kept on giving direct patient health care. Hospital pharmacist’s specialists partake in antimicrobial stewardship programs; accordingly are straightforwardly engaged with arranging and reacting to microorganism episodes. Clinical Pharmacist gives event?driven drug care administrations to COVID?19 patients. Clinical Pharmacist likewise intently screen drugs/drug classes with more security concerns. On the other hand ICU attendants, doctors, and respiratory advisors, emergency clinic drug specialists have been essential for the COVID-19 endeavors. Pharmacist associations or committees such as Pharmacy Council of India and some other private associations have given their rules and in this publication, a few worldwide instances of drug specialists' part in the COVID 19 are being examined. All Pharmacy officers are accomplishing by their work by keeping in see their laws and guidelines. Keywords: Frontline worrier, Community pharmacists, Hospital pharmacists, Clinical pharmacists

Novel coronavirus (2019-nCoV) is respiratory syndrome virus originated from Wuhan, Hubei province, China. The disease is infected by inhalation, fever, cough, fatigue in Human and infected to Animals by inter or intra Transmission like dog, cat, pig, cow. Human nCoV is single stranded, spherical, wrapped RNA, shaped glycoprotein and pleomorphic. The scientists found many coronavirus was detectable on different types of Surfaces. WHO and Ministry of AYUSH recommends some guidelines for preventive health measures and boosting immunity reference to respiratory health. Keywords: 2019-nCOV, 2019-nCOV, Preventions, Symptoms, Preventive health measures.

ISO 9000 is a widely used quality management standard in the world. The review of literature has shown the Overview of ISO 9000 series of standards.ISO 9000 application oppose the philosophy of Quality Management Systems (QMS) Approach, control an organization in order to continually improve the effectiveness and efficiency of its performance is known as quality management system. The principles of Quality management systems Fundamentals and vocabulary and in ISO 9004:2000 and Guidelines for performance improvements. Keywords: ISO 9000, ISO, Quality Management Systems (QMS), Principles.