Shilpa Mishra

Abstract

Villous adenomas are known to occur in gastrointestinal tract; however, they are very rare in female genital tract. The pathogenesis is unclear but their origin from cloacal remnants has been hypothesized. Here we report a rare incidental case of primary villous adenoma with high grade dysplasia arising from vaginal vault in a 28-year-old female who presented with abnormal vaginal bleeding. The importance of reporting this lies in its pre-malignant behaviour and benign looking clinical appearance. Keywords: Villous adenoma, Vaginal mass, Vaginal vault

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Abstract

Fibrocartilaginous dysplasia (FCD) or massive cartilaginous differentiation in fibrous dysplasia are interchangeably used terms. It is a rare variant of fibrous dysplasia (FD) which is benign, lytic, and expansile bone lesion and causes progressive deformity in the bones and may lead to pathological fracture. Radiologically, FCD may confused with cartilaginous benign and malignant bone tumours. FCD usually shows calcification in imaging. Surgical curettage or corrective osteotomy and histopathological examination of these lesions is necessary to differentiate it from other cartilaginous tumours. Here we report case of fibrocartilaginous dysplasia of distal femur in a 4-year-old male child.   Keywords: Fibrocartilaginous Dysplasia, Fibrous Dysplasia.

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Abstract

Morular metaplasia is an unusual type of metaplastic change, often observed in numerous endometrial lesions. It has been considered a variant of squamous metaplasia and has a mulberry-like appearance. Morular metaplasia lacks the characteristic histopathological features of conventional squamous differentiation and hence their relationship with each other has not been clearly defined. These lesions are usually seen along with pre-malignant and malignant glandular lesions of endometrium. Their presence in normal endometrium or benign endometrial polyps is rare, however it can cause a diagnostic dilemma. We present a case of a 39-year-old female who underwent hysteroscopic removal of an endometrial polyp. On gross examination it was a well-defined tan white lesion. Microscopy showed cystically dilated glands along with foci of extensive morular metaplasia. There was no evidence of any atypia/ dysplasia or malignancy in the material studied. It is important to report morular metaplasia in benign localised endometrial lesions due its usual association with endometrial hyperplasia/ atypical hyperplasia or endometrial endometrioid carcinoma. The patient requires regular follow up with clinico-radiological correlation in view of risk of presence of other coexisting lesions in these cases.    Keywords: Endometrial metaplasia, squamous metaplasia, morular metaplasia, endometrial polyp

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