G Sreenivasulu

Abstract

Aim: To clinically and microbiologically evaluate the association of periodontitis and pre-diabetes. Materials and Methods: The trial was designed as a randomized controlled clinical trial with a sample size of total of 100 with 1:1 gender ratio. Test group taken were patients with chronic periodontitis with prediabetes and Control group were patients with periodontitis without prediabetes. Body mass index (BMI), Periodontal Probing Depth (PPD),Bleeding on probing (BOP),Clinical Attachment Loss(CAL) using UNC colour coded periodontal probe were recorded. The microbial load in pre-diabetes patients was assessed using samples collected from the periodontal pockets ?5mm. Fasting Blood sugar (FBS), Post Prandial blood sugar (PPBS), Fasting Insulin were recorded at baseline, 6 weeks,12 weeks and after Non-surgical periodontal therapy (SRP) after taking consent from the patient. The data collected were entered into Microsoft excel 2018. Statistical analysis was done using IBM SPSS Statistics for Windows, Version 27.0. Armonk, NY: IBM Corp. Descriptive analyses were done. Student’s t-test, repeated measures of ANOVA were used for determination of the significance of HOMA-IR, HOMA- β mean differences between and within the groups. Results: In both test and control groups, there was a significant difference (p Conclusion: There is a significant association between prediabetes state and periodontitis. Early diagnosis of periodontitis and a proper treatment in prediabetic group can prevent the progression of prediabetic condition to diabetes and vise versa.   Keywords: Periodontitis, Prediabetes, Insulin resistance, β cell dysfunction

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Abstract

Background:  Periodontitis is often associated with diabetes and might be considered one of the chronic complications of diabetes mellitus (DM), both in Type 1 (T1DM) and Type 2 (T2DM). This cross sectional study was designed to evaluate the possible association between clinical periodontal disease status and glycemic levels in diabetes patients (T2DM) among the population of city Hyderabad, INDIA. Materials and Methods:  A total of 200 individuals were examined and out of which 179 were enrolled fulfilling the selection criteria were initially given a health questionnaire to gather information regarding their demographic data, oral hygiene practices. Based on Fasting plasma glucose (FPG) levels, they were grouped into: Good, Moderately and Poorly controlled Type 2 Diabetic patients. Oral hygiene index-simplified, CPI and clinical attachment level (CAL), Tooth mobility and Tooth loss due to mobility were evaluated. Results:  Nearly Half the individuals have good glycemic control. (47.5% are Conclusion:  Patients with high plasma sugar levels were more susceptible for severe periodontal disease. CPI values and mobility of teeth was less in subjects with FPG   Keywords: Fasting plasma glucose, Community periodontal index, Oral hygiene status, Periodontitis

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