Serum paraoxonase – Marker of alcoholic liver cirrhosis

Authors : B Jyotchna Devi, B Jyotchna Devi, V Uma Lakshmi, V Uma Lakshmi, Naazia Arifuddin, Naazia Arifuddin, J Rama Rao, J Rama Rao, Ch Kiranmai, Ch Kiranmai

DOI : 10.18231/2394-6377.2018.0109

Volume : 5

Issue : 4

Year : 0

Page No : 513-516

Serum Paraoxonase is an esterase, along with Apolipoprotein A1 and Clusterin (Apolipoprotein J), PON 1 is associated with HDL. This study was done to assess the significance of serum Paraoxonase as an biomarker along with standard liver function tests in evaluating alcoholic cirrhosis. Serum Paraoxonase levels was estimated in 30 patients diagnosed with alcoholic cirrhosis and 30 healthy blood donors. Paraoxonase levels were significantly lower in cases as compared with controls (P<0> Conclusion : Serum Paraoxonase is sensitive marker for patients with alcoholic liver disease and oxidative stress and should be included as an additional parameter along with the other parameters in liver function tests.

Keywords: Alcoholic cirrhosis, Antioxidant, Paraoxonase, Liver function tests.


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