A study presenting the analysis of co-infection of chikungunya and dengue virus in a microbiology laboratory at tertiary care hospital in western India

Authors : Hetvi Chawda, Hetvi Chawda, Madhulika Mistry, Madhulika Mistry, Tanavi Chaudhari, Tanavi Chaudhari

DOI : 10.18231/j.ijmr.2019.035

Volume : 6

Issue : 2

Year : 2019

Page No : 162-165

Coinfection means simultaneous infection by two or more virus. Dengue and Chikungunya are viral infections caused by RNA virus (arbovirus). The transmitting vector for both viruses is Aediesaegypti. Human co-infection with DENV and CHIKV have been reported in India since 1967. DENV and CHIKV share a number of similarities in clinical presentation which includes seasonal transmission cycle. This study was carried out in Virology Department, PDU Medical College, Rajkot. A total of 3810, 2122 and 1605 hospitalized patients were serologically screened for DENV, CHIKV and both, respectively between July and October 2017 by IgM Capture ELISA. Co-infection was defined as a positive IgM assay for both infections.60 (3.73%) were IgM positive for both DENV and CHIKV. 474 (12.44%) were mono-infected with DENV and 721 (33.97%) were mono-infected with CHIKV. Simultaneous infection with Dengue and Chikungunya viruses is having more severity than single infection. Early detection and time bound Notification of the positive cases help to reduce the morbidity and mortality rate and help the health authorities to execute effective measures for prevention and control of diseases. This will also help in increasing vigilance before any epidemic.

Keywords: Co infection, Dengue, Chikungunya, ELISA.

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