Reversal of the anticoagulant effect of direct thrombin inhibitor dabigatran etexilate in acute ischemic stroke and intracranial hemorrhage using idarucizumab – A case study

Authors : Ashutosh N Shetty, Nasli R Ichaporia, Amod Tilak, Sonesh Kalra

DOI : 10.18231/j.ijn.2019.028

Volume : 5

Issue : 3

Year : 2019

Page No : 176-180

The non-Vitamin K oral anticoagulants (NOACs) help prevent stroke in patients of atrial fibrillation.
However, management of patients on NOACs in emergency situations is a challenging prospect.
Idarucizumab is approved globally as well as in India as the specific reversal agent for dabigatran. We
report two cases with successful reversal using Idarucizumab in acute ischemic stroke and intracranial
hemorrhage.

Keywords: Atrial fibrillation, Bleeding, India, Stroke.


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