Authors : Harvinder Singh, Maninder Kaur, G K Bedi, R P S Sibia, Divmehar Kaur
DOI : 10.18231/j.ijcbr.2020.068
Volume : 7
Issue : 3
Year : 2020
Page No : 317-319
Introduction: Elevation of serum ferritin levels leads to serious complications. Increased serum
ferritin levels leads to increased oxidative stress, further leading to inflammation, endothelial damage and
consequently increasing the risk of hypertension.
Aim: The aim of the present study was to estimate and compare serum ferritin levels in the hypertensive
patients and control group.
Material and Methods: The present study was a hospital-based observational and analytical study.
The study was conducted over a period of 1 year on 102 patients. The study group comprised of 51
patients (diagnosed with hypertension), and the control group comprised of 51 (age and gender matched)
individuals. The levels of serum ferritin were analysed by the Sandwich ELISA method.
Result: The results of the present study show that, the mean value of serum ferritin was 293.27 ± 219.84
ng/ml in study group and 72.23 ± 29.75 ng/ml in control group. The mean SBP was 151.45 ± 14.77 mm/Hg
in study group and 109.88 ± 5.43 mm/Hg in control group. The mean DBP was 95.56 ± 7.46 mm/Hg in
study group and 72.43 ± 2.97 mm/Hg in control group. The results of the present study indicate that the
difference between the mean serum ferritin and mean SBP, mean DBP among the study group and control
group was found to be significant statistically (p=<0>
Conclusion: The present study concluded that there exists a positive correlation between the mean serum
ferritin levels and hypertension among the study group (patients with hypertension).
Keywords: Systolic blood pressure, Diastolic blood pressure, Oxidative stress.