Authors : Sunil Chaudhry, Sunil Chaudhry
DOI : 10.18231/j.agems.2020.013
Volume : 7
Issue : 2
Year : 2020
Page No : 80-85
Idiopathic pulmonary fibrosis (IPF) is an interstitial lung disease characterised by chronic, progressive scarring of the lungs. It is a relatively rare disease, afflicting those 50–70 years of age, slightly more common among men than women, without racial predilection. The most common complaint is progressive shortness of breath. Pulmonary function testing reveals a restrictive Ventilatory defect with a diminished diffusion capacity Despite advances in therapy progress has been challenged by a poor understanding of pathological mechanisms and patient heterogeneity, including variable progression. The outcome of the disease is poor and patients often succumb to mortality in few years.
Keywords: Smoking, Hypersensitivity, Autoimmune, Occupation, Idiopathic pulmonary fibrosis nintedanib, Pirfenidone.