A real world retrospective analysis of comparison of effectiveness and safety of mometasone furoate and fluticasone propionate in the management of eczema and dermatitis

Authors : R D Kharkar, R D Kharkar, Dhiraj Dhoot, Dhiraj Dhoot, Harshal Mahajan, Harshal Mahajan, Hanmant Barkate, Hanmant Barkate

DOI : 10.18231/j.ijced.2021.023

Volume : 7

Issue : 2

Year : 2021

Page No : 120-124

Introduction: Contact dermatitis is one the commonest dermatological condition which is managed by topical corticosteroids. Mid potent topical corticosteroids are commonly prescribed but there is no any comparative data between mometasone furoate and fluticasone propionate in the management of dermatitis.
Materials and Methods: A real world retrospective study was conducted across India to compare the clinical assessment of mometasone 0.1% cream and fluticasone 0.005% cream in the management of contact dermatitis at 236 dermatology clinics.
Results: A data of 1106 patients were included in this analysis in which 598 were included in mometasone group while 508 in fluticasone group. At the end of 2 weeks, 216 patients (36.1%) in mometasone and 129 patients (25.4%) in fluticasone group achieved complete clearance of symptoms (p<0> Conclusion: Both, mometasone furoate and fluticasone propionate were effective and safe in treatment of eczema/dermatitis. But mometasone furoate had shown significantly better effectiveness as compared to fluticasone in all predisposing factors for the disease.

Keywords: Dermatitis, Mometasone, Fluticasone, Real world.


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