Intranasal midazolam versus intranasal dexmedetomidine as premedication in paediatric patients: A comparative study

Authors : Vimal Dangi, Vimal Dangi, Sushil Chand Verma, Sushil Chand Verma, Vinayak Gour, Vinayak Gour

DOI : 10.18231/j.ijca.2021.115

Volume : 8

Issue : 4

Year : 2021

Page No : 532-536

Background: Preanesthetic medication is important among the paediatric patients undergoing surgeries. A good preanesthetic medication reduces the anxiety and the post-operative pain among paediatric patients.
Materials and Methods: A randomised controlled trial was done to compare the two groups of Dexmedetomidine, and Midazolam given as preanesthetic medication intranasally.
Results: Both the groups had comparable baseline values before premedication but there was a significant difference in the vital parameters of heart rate and systolic blood pressure after medication. The mean Parental Separation Anxiety Scale was found to be 1.4 ± 0.85 and 2.5 ± 0.98 among Dexmedetomidine and Midazolam group respectively. This was found to be significant (p < 0> Conclusion: Dexmedetomidine when given as preanesthetic medication intranasally significantly controls the vitals within the normal range and produces better parental separation anxiety scores and mask acceptance scores as compared to Midazolam.


Keywords: Dexmedetomidine, Gynaecological surgeries, Clonidine.


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