Predictive role of lymphocyte subsets in COVID-19 patients

Authors : Sunil Vitthalrao Jagtap*, Pranjal Setul Shah

DOI : 10.18231/j.achr.2023.018

Volume : 8

Issue : 2

Year : 2023

Page No : 73-75

Coronaviruses: CoVs, is related to the family of Coronaviridae. The SARS-CoV-2: severe acute respiratory syndrome coronavirus 2, is unique strain of RNA viruses. The recent pandemic caused by coronavirus SARS-CoV-2 is threatening the human population worldwide. The patients with severe forms may develop severe pneumonia and may fatal. The COVID-19 range from a mild to severe form., SARS-CoV-2 infected patients shows severe lymphopenia in about 2/3 cases. In patients with severe disease lymphocyte subset counts in the peripheral blood owere significantly reduced. The predictor biomarker for assessing disease and monitoring with SARS-CoV-2 infection is done by peripheral blood CD4+ and CD8+ T cells' count. It is necessary to do more studies on larger populations and detail understanding of Tell immunity and for new treatment strategies.
 

Keywords: Coronaviruses, COVID­19 biomarkers, CD4+ and CD8+T cells, Prognostic role T lymphocytes


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