Authors : Ms. Sonawane R.R. Ms. Suryavanshi P.S. Ms. Somvanshi S.R. Dr. Kapse S.N. Mr. Patil R. N. Mr. Raut H.V.
DOI : 10.53555/cmnmdq73
Volume : 31
Issue : 11
Year : 2024
Page No : 1484-1491
Background: Breast cancer is the most commonly diagnosed malignancy in women and a leading cause of cancer-related mortality worldwide. Despite advancements in diagnostic and therapeutic strategies, breast cancer remains a significant clinical challenge due to its heterogeneity and the adverse effects of conventional treatments. The use of traditional herbal medicine, known for its minimal side effects and efficacy, offers a promising alternative. Material & Methods: Aerial parts of Anethum graveolens seeds and Spinacia oleracea leaves were extracted using the Soxhlet extraction method. This study investigates the anti-mammary carcinoma potential of Anethum graveolens (dill) seeds and Spinacia oleracea (spinach) leaves, known for their bioactive compounds with anti-cancer properties. Result & Discussion: At the different doses (10 to 100 µg/ml) of polyherbal extracts carried out for anticancer activity against MCF-7 cell line., the polyherbal extracts showed good activity against breast cancer cell line when compared with the standard drug 5 FU. These findings highlight the anti-cancer potential of polyherbal extract of Anethum graveolens seeds and Spinacia oleracea leaves as natural therapeutic agents for the management of mammary carcinoma.