Consequence of smoking on hematological parameters in apparently healthy medical students

Authors : Mohammed A. Al Mufarah, Naif O. Alharbi, Anfal Y. Aqeeli, Rawan F. Bokhedher, Zahraa Al Mohsen

DOI : 10.18231/j.ijmmtd.2022.056

Volume : 8

Issue : 4

Year : 2022

Page No : 288-293

Background: One of the greatest causes of death in the globe is tobacco cigarette smoking. Smoking affects hematological markers both acutely and chronically. The current study's objective was to evaluate the severity of the negative effects of cigarette smoking on biochemical traits in healthy smokers.
Materials and Methods: This study included 280 participants, only 56 smokers and 100 non-smokers. They were smoking for three years, the smokers regularly smoked 10 to 20 cigarettes per day. The fully automatic hematological analyzer CELL-DYN 3700 examined the total number of blood cells.
Results: White blood cells (p0,001), hemoglobin (p=0,042), mean corpuscular volume (p=0,001), and mean corpuscular hemoglobin concentration (p0,001) were all considerably greater in the smokers. No other measured metrics varied considerably from one another. Red blood cells, white blood cells, hemoglobin, hematocrit, and mean corpuscular hemoglobin were all significantly higher (p0,001) in male smokers compared to female smokers after smoking cigarettes.
Conclusion : Our study concluded that smoking cigarettes continuously has severe negative effects on hematological variables, including hemoglobin, white blood cell count, mean corpuscular volume, mean corpuscular hemoglobin concentration, red blood cell count, and hematocrit. These modifications may be linked to an increased risk of polycythemia vera, atherosclerosis, chronic obstructive pulmonary disease, and/or cardiovascular diseases.
 

Keywords: Hematological parameters, Cigarette smoking, Healthy people


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