Evaluation and clinical management of drug-drug interactions in hypertensive patients associated co-morbidities: A study in general medicine and ICU ward

Authors : Rohit Kumar, Avinash Teli, Pooja Rathore, Vishal Kumar, Sharookh Ali

DOI : 10.18231/j.jpbs.2023.010

Volume : 11

Issue : 1

Year : 2023

Page No : 57-65

This comparative study aims to evaluate and compare the clinical management of drug-drug interactions (DDIs) in hypertensive patients with associated co-morbidities, specifically focusing on the practices in general medicine and ICU ward settings. Hypertensive patients commonly experience co-morbidities that require multiple medications, increasing the risk of DDIs and subsequent adverse events. Understanding the current evaluation and management strategies for DDIs in these patient populations is essential for optimizing patient outcomes. This research investigates the approaches employed in general medicine and ICU wards, including DDI identification, assessment, and intervention methods. By comparing these practices, the study aims to identify potential variations, challenges, and areas for improvement in DDI management across these clinical settings. The findings of this study will contribute to the development of evidence-based guidelines and recommendations for enhancing the clinical management of DDIs in hypertensive patients with co-morbidities, ultimately improving patient safety and therapeutic outcomes.


Keywords: Drug- drug interactions, Hypertension, Co-morbidities, Multidisciplinary approach, General medicine, ICU, Patient Safety, Therapeutic outcomes


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