Screening of Coxsackie B virus infection among patients with myocarditis and dilated cardiomyopathy using Serion Elisa classic Coxsackie virus IgM in Chennai, Tamilnadu, South India

Authors : K. Bharathi, Jeevan Malaiyan

DOI : 10.18231/2394-5478.2018.0032

Volume : 5

Issue : 2

Year : 0

Page No : 154-157

Almost 70% of the myocarditis and dilated cardiomyopathy (DCM) cases are found to be caused by Enterovirus genus, the majority of these infections were caused by coxsackie virus B (CVB) group. There is no recent data available on extra-intestinal infection particularly myocarditis and DCM caused by this virus in south India. Presence of IgM antibody specific for CVB in myocarditis and DCM patients were detected using SERION ELISA. The prevalence of Coxsackie B virus among myocarditis and dilated cardiomyopathy patients was found to be 75.75% when tested using an immunoassay specific for IgM antibodies. The mortality rate among study population is found to be 6%.

Keywords: Coxsackie B virus, Myocarditis, Dilated cardiomyopathy, Serion elisa


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