Authors : Muzafar Amin, Vidya Pai,, Sumaira Qayoom, Syed Arshi, Syed Khurshid
DOI : 10.18231/2394-5478.2018.0088
Volume : 5
Issue : 3
Year : 0
Page No : 425-429
Purpose: To study the biofilm formation and to examine the correlation between antibiotic resistance and biofilm formation among the clinical isolates of Acinetobacter.
Materials and Methods: A total of 43 isolates of Acinetobacter collected from samples like peripheral venous catheter tips, urine from Foley’s catheter, central venous catheter tips and endotracheal tube aspirates were preserved and processed. The tube method was performed to qualitatively detect Biofilm production. Antimicrobial susceptibility was done as per CLSI guidelines.
Place of Study and Study Period: Yenepoya medical college, Mangaluru and June 2015 to December 2015.
Study Design: Prospective
Results: Out of 43 isolates of Acinetobacter, 26(60%) showed biofilm production, among which 19 isolates (73%) were Multidrug resistant (MDR) and only 7 isolates (27%) were Non-MDR. Highest sensitivity was seen to colistin (100%) followed by imipenem (73.7%) and least sensitivity to ampicillin (0%) followed by ciprofloxacin (3.8%).
Conclusion: Antibiotic resistance was found to be significantly higher among biofilm producing Acinetobacter isolates than nonbiofilm isolates. Routine and advanced studies of the biofilm production will help in making better usage of the invasive devices with less critical complications.
Keywords: Biofilms, Acinetobacter, Multidrug resistance.