Authors: Richa Surit, Ravi Shekhar*, Jiut Ram Keshari, Pritam Prakash, Sweta Kumari
Background: Type 2 Diabetes mellitus (DM) is a chronic metabolic disorder. India has 72.9 million people living with diabetes (8.8%). The Cardio Vascular Disease (CVD) risk increases in patients with Type 2 diabetes. The Non-HDL-C level includes cholesterol carried in several atherogenic lipoproteins. The estimation of non-HDL-C may provide a better means to follow these patients toward their treatment goals. The study compares the level of non-HDL-C in non diabetic, pre-diabetic and diabetes patients and their occurrence of dyslipidemia. Materials and Methods: The study group included 1418 patients and were grouped as – Non diabetic, pre-diabetic and Diabetic, having age group of 20 to 85 years. The Male:Female ratio was 1.9:1. Their blood samples were analysed in Clinical Biochemistry Laboratory on automated chemistry analyzer with quality checks. Result: The Non Diabetic group (HbA1c6.4%) had 538 patients and its non HDL-C was 148±4.27 mg/dl. Conclusion: This study showed the groups, pre-diabetic and diabetic, had Non-HDL-C >130mg/dl. An increase in Non-HDL-C levels is associated with increased risk of CVD according to Adult Treatment Panel (ATP) III guidelines. Keywords: HbA1c, Non- HDL- C, LDL- C, DM, CVD.
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