Authors : Richa Surit, Ravi Shekhar, Jiut Ram Keshari, Pritam Prakash, Sweta Kumari
DOI : 10.18231/j.ijcbr.2023.019
Volume : 10
Issue : 2
Year : 2023
Page No : 118-122
Background: Type 2 Diabetes mellitus (DM) is a chronic metabolic disorder. India has 72.9 million people living with diabetes (8.8%). The Cardio Vascular Disease (CVD) risk increases in patients with Type 2 diabetes. The Non-HDL-C level includes cholesterol carried in several atherogenic lipoproteins. The estimation of non-HDL-C may provide a better means to follow these patients toward their treatment goals. The study compares the level of non-HDL-C in non diabetic, pre-diabetic and diabetes patients and their occurrence of dyslipidemia.
Materials and Methods: The study group included 1418 patients and were grouped as – Non diabetic, pre-diabetic and Diabetic, having age group of 20 to 85 years. The Male:Female ratio was 1.9:1. Their blood samples were analysed in Clinical Biochemistry Laboratory on automated chemistry analyzer with quality checks.
Result: The Non Diabetic group (HbA1c<5>6.4%) had 538 patients and its non HDL-C was 148±4.27 mg/dl.
Conclusion: This study showed the groups, pre-diabetic and diabetic, had Non-HDL-C >130mg/dl. An increase in Non-HDL-C levels is associated with increased risk of CVD according to Adult Treatment Panel (ATP) III guidelines.
Keywords: HbA1c, Non- HDL- C, LDL- C, DM, CVD.