Vineet Banga

Abstract

Rosai-Dorfman disease (Sinus Histiocytosis with Massive Lymphadenopathy) is a rare disorder characterized by overproduction (proliferation) and accumulation of histiocytes in the lymph nodes of the body causing lymphadenopathy, most often involving neck. In some cases, abnormal accumulation of histiocytes may occur in other areas of the body besides the lymph nodes (extra nodal). These areas include the skin, central nervous system, kidney, and digestive tract. The case is being reported as a rare case involving isolated axillary lymph node and was diagnosed on FNAC.   Keywords: Sinus Histiocytosis with Massive Lymphadenopathy (SHML), Rosai Dorfman Disease (RDD), FNAC, Axillary Lymph Node

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Abstract

Fibroepithelial polyp (FEP) or acrochordon are skin tags frequently arising in skin folds in locations like the neck, axilla, perineum, eyelids and chest wall. Only 7 cases of FEP of the nipple have been reported in the literature so far. Here we report such a rare case diagnosed on FNAC and Biopsy.   Keywords: Fibroepithelial polyp, Acrochordon, Breast nipple

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Abstract

Introduction: Patients of Covid 19 infections present with different severity. Levels of D Dimer in these patients can be correlated with disease severity for management and prognosis. Aims and Objectives: To evaluate the usefulness of D-Dimer levels in blood to correlate with disease severity in COVID 19 patients. Materials and Methods: Retrospective study was done in Department of Pathology of Secondary Care hospital that became designated covid hospital from May 2021 to June 2021 on 60 COVID 19 positive admitted patients. D dimer levels were analysed and correlated with clinical severity of disease. Results: Out of total 60 patients, 33 were in mild, 23 in moderate and 4 were in severe category. In mild cases D Dimer varies from 43 ng/ml to 183 ng/ml. In moderate cases D Dimer varies from 270 ng/ml to 991 ng/ml. In severe cases D Dimer varies from 1043 ng/ml to 2463 ng/ml. The study suggests cut off levels for D Dimer as up to 200 ng/ml for mild, 200-1000 ng/ml for moderate and more than 1000 ng/ml for severe category in COVID 19 patients. Conclusion: D dimer helps in identifying severe disease and can be used as an essential biomarker in developing the management protocol for COVID 19 patients.   Keywords: Covid 19, D Dimer, Prognostic indicator.

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Abstract

Scrotal calcinosis is a rare condition characterised by single or multiple hard, painless nodules in the scrotal skin. It is uncommon and subtype of calcinosis cutis. It appears mainly in men aged 20?40 years of age as hard, yellowish nodules varying in size (1 mm to several centimetres). They are usually asymptomatic; however, may be complicated with heaviness, itching or discharge. FNAC (Fine needle aspiration cytology) can prove to be a useful tool for diagnosis of this rare disorder. A diagnosis by FNAC may at times be comforting for the patient and the treating Doctor and can help avoid unnecessary surgery. Reports on this issue are sparse and thus we are reporting uncommon condition of scrotal calcinosis diagnosed on FNAC rarely used to diagnose this condition.   Keywords: Scrotal calcinosis, FNAC, Histopathology

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