D Dimer – Prognostic indicator for disease severity in patients hospitalised with COVID 19

Authors : Vineet Banga, Vineet Banga, Stuti Jain, Stuti Jain

DOI : 10.18231/j.ijpo.2021.096

Volume : 8

Issue : 4

Year : 2021

Page No : 461-464

Introduction: Patients of Covid 19 infections present with different severity. Levels of D Dimer in these patients can be correlated with disease severity for management and prognosis.
Aims and Objectives: To evaluate the usefulness of D-Dimer levels in blood to correlate with disease severity in COVID 19 patients.
Materials and Methods: Retrospective study was done in Department of Pathology of Secondary Care hospital that became designated covid hospital from May 2021 to June 2021 on 60 COVID 19 positive admitted patients. D dimer levels were analysed and correlated with clinical severity of disease.
Results: Out of total 60 patients, 33 were in mild, 23 in moderate and 4 were in severe category. In mild cases D Dimer varies from 43 ng/ml to 183 ng/ml. In moderate cases D Dimer varies from 270 ng/ml to 991 ng/ml. In severe cases D Dimer varies from 1043 ng/ml to 2463 ng/ml. The study suggests cut off levels for D Dimer as up to 200 ng/ml for mild, 200-1000 ng/ml for moderate and more than 1000 ng/ml for severe category in COVID 19 patients.
Conclusion: D dimer helps in identifying severe disease and can be used as an essential biomarker in developing the management protocol for COVID 19 patients.
 

Keywords: Covid 19, D Dimer, Prognostic indicator.


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