Authors: Anshul Singh
Hepatoid adenocarcinoma (HAC) is a very rare malignant tumor of extrahepatic origin which is characterized by having foci with features of both hepatocellular differentiation as well as adenomatous differentiation. It is most commonly seen in the stomach, however, few cases of HAC originating in the ovary, small intestine, colon, lung, uterus, pancreas, gallbladder, oesophagus and periampullary region have also been reported. Interestingly, it morphologically and functionally resembles Hepatocellular carcinoma, which can make the diagnosis challenging. Identification of HAC is necessary as it is associated with a dismal prognosis. We report here a case of a metastatic hepatoid adenocarcinoma of an unknown primary presenting in the ascending colon with both hepatoid and mucinous adenocarcinomatous areas on morphology. Keywords: Gastrointestinal tract, Hepatic like, Tumor.
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