Gunjan Chadha

Abstract

Purpose: To report a case on unusual presentation of Axenfeld Reiger (A-R) syndrome. Observation: Axenfeld Rieger syndrome commonly presents with prominent Schwalbe’s line near the limbus. Presentation with displaced Schwalbe’s line is rarely reported. We report 2 cases who presented with bilaterally displaced Schwalbe ring as strange cord like structure in anterior chamber with iris tissue adhesions. Conclusion: Axenfeld – Reiger syndrome is an autosomal dominant disease with ocular findings involving cornea (megalocornea), iris (iris atrophy,correctopia) and angle (anterior insertion of iris, prominent Schwalbe line). We report unsual case of detached Schwalbe’s line with iris tissue adhesions in anterior chamber A-R syndrome.   Keywords: Axenfeld rieger syndrome, Schwalbe’s line.

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Abstract

Purpose: To evaluate the effect of platelet rich plasma as treatment modality in various etiologies of dry eye. Materials and Methods: A prospective study was conducted at a tertiary eye care hospital on 65 eyes of 40 patients for a duration of three years, who presented with the complaints of dry eye due to various etiologies. Platelet rich plasma (PRP) was made from the patient’s serum and they were advised to be instilled in topical eyedrop form six times a day. Results: The study included 29 men and 11 women. The mean age was 40yrs (34.45±15.17), range 10 – 60 years. Dry eye symptoms like burning sensation, itching, dryness, blurred vision and redness were studied and were found to be significantly reduced (p=0.0001)post treatment with PRP after one month. The improvement in symptoms was most likely due to indirect reduction of inflammation. Around 30.7% eyes had improvement in visual acuity of atleast one line. The Schirmer’s test also showed improvement with Schirmer values before treatment being 5.34mm± 2.18 mm to 15.90 mm±7.75mm after treatment. Around 46.87% right eye and 39.9% left eye also had improvement with tear break up time more than 10 sec. Conclusion: The use of PRP eye drops for the treatment of various etiologies of dry eye was shown to be effective in reducing the symptoms of dry eye without any significant complications. Keywords: Corneal erosions, Dry eye, Platelet rich plasma, Tear film Serum.

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Abstract

Purpose: to report a case of PAM with atypical presentation Observations: We are reporting a case of a 45 years old male who presented to the outpatient department of Ophthalmology with complaints of sudden onset watering and foreign body sensation in the right eye. Detailed slit lamp examination revealed an elevated pigmented lesion of the conjunctiva in the nasal quadrant extending up to 2 clock hours. Excision biopsy was done and histopathological examination found the lesion to be moderate grade dysplastic conjunctival PAM. Conclusions and importance: Primary acquired melanosis (PAM) is an acquired disorder of the conjunctiva characterized by a flat brown pigmentation of the conjunctival epithelium. It may be analogous to lentigo maligna—a preinvasive epidermal pigmentation of skin. It presents as a unilateral patchy area of conjunctival pigmentation mostly seen in middle aged or elderly light skinned individuals with a potential for malignant transformation. Keywords: Conjunctival nevus, Malignant melanoma, Primary acquired melanosis.

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