Authors: Pampa Reddy B Kollur, Raghunandana R, Girish M Desai, Netravati Sajjan, Sunilkumar Biradar*
Background: Ischemic health disease is a major health and a modern epidemic which is increasing in India. Dyslipidemia is a major risk factor for atherosclerosis. Serum adenosine deaminase activity is associated with coronary artery disease. Aims and Objectives: The present work was done to understand the relation of serum adenosine deaminase activity with dyslipidemia in ischaemic heart disease. Materials and Methods: This cross-sectional study comprised 200 subjects; healthy and myocardial infarction. Serum ADA and lipids were estimated. Obtained data was statistically analysed. Result: Increase in serum ADA activity correlating with dyslipidemia was found in Myocardial infarction subjects. Discussion: Increased ADA has role in LDL oxidation, dyslipidemia, foam cell transformation etc. leading to atherosclerosis and ischemic heart disease. Conclusion: Adenosine deaminase has a crucial role in the evolution of ischemic heart disease through dyslipidemia and coronary artery disease. Keywords: Adenosine deaminase, Ischemic heart disease, Atherosclerosis, Lipids
Open full article page