Authors : Pampa Reddy B Kollur, Raghunandana R , Girish M Desai, Netravati Sajjan, Sunilkumar Biradar
DOI : 10.18231/j.ijpo.2022.031
Volume : 9
Issue : 2
Year : 2022
Page No : 128-131
Background: Ischemic health disease is a major health and a modern epidemic which is increasing in India. Dyslipidemia is a major risk factor for atherosclerosis. Serum adenosine deaminase activity is associated with coronary artery disease.
Aims and Objectives: The present work was done to understand the relation of serum adenosine deaminase activity with dyslipidemia in ischaemic heart disease.
Materials and Methods: This cross-sectional study comprised 200 subjects; healthy and myocardial infarction. Serum ADA and lipids were estimated. Obtained data was statistically analysed.
Result: Increase in serum ADA activity correlating with dyslipidemia was found in Myocardial infarction subjects.
Discussion: Increased ADA has role in LDL oxidation, dyslipidemia, foam cell transformation etc. leading to atherosclerosis and ischemic heart disease.
Conclusion: Adenosine deaminase has a crucial role in the evolution of ischemic heart disease through dyslipidemia and coronary artery disease.
Keywords: Adenosine deaminase, Ischemic heart disease, Atherosclerosis, Lipids