Authors : Jyoti Batra, Jyoti Batra, Sudeep Kumar, Sudeep Kumar, Manisha Arora, Manisha Arora, Sumesh Prasad Sah, Sumesh Prasad Sah, Roshan Kumar Mahat, Roshan Kumar Mahat
DOI : 10.18231/2455-1732.2018.0019
Volume : 4
Issue : 2
Year : 0
Page No : 82-86
Introduction: BMI is associated with Vitamin D in pre and postmenopausal women. As the estrogen level decreases during menopause, this promotes hypovitaminosis D. The present study assessed Vitamin D status and found its correlation with BMI in healthy pre- and postmenopausal women.
Materials and Methods: This cross-sectional study was conducted on 100 pre-menopausal and 100 postmenopausal women. Blood samples were collected for estimation of Vitamin D by fully automated Chemi Luminescent Immuno Assay. Statistical analyses were done by using Graphpad Prism 6 and Pearson correlation coefficient was computed between Vitamin D and BMI.
Results: The mean levels of weight and BMI were increased significantly in post-menopausal women as compared to premenopausal women and the mean level of Vitamin D was decreased significantly in postmenopausal women as compared to premenopausal. In the present study, we observed that the BMI is significantly and negatively correlated with Vitamin D concentration in both pre (r=-0.549) and postmenopausal (r=-0.736) women and it was statistically significant.
Conclusion: Vitamin D deficiency is prevalent in pre- and postmenopausal with BMI greater than 25 kg/meter2 and the decrease in Vitamin D was more in postmenopausal women as compared to premenopausal women and the Vitamin D was negatively associated with BMI in both pre and postmenopausal women.
Keywords: Postmenopausal, BMI, Vitamin D, Estrogen, Osteoporosis