Role of C-reactive protein (CRP) in determining neonatal infections

Authors : Chandrahas Godbole, Chandrahas Godbole, Poonam Lalla, Poonam Lalla

DOI : 10.18231/j.ijcbr.2019.065

Volume : 6

Issue : 3

Year : 2019

Page No : 294-298

CRP is one of the reliable diagnostics marker used in diagnosis of Neonatal Sepsis that has been widely
available, most studied and preferred over the newly emerging infection markers. In this study, we have
studies that even CRP assay has proven to be less time consuming and effective analyzing samples of
neonates who are already on antibiotics treatment. In our study 40 neonates were proved to have neonatal
sepsis which was based on signs and symptoms shown by patient. The other studies have revealed, CRP
biochemistry assay have high sensitivity and specificity as compare to HSS for diagnosis of NS; we also
got 100% sensitivity and specificity for CRP testing. Hence we concluded that CRP is a good diagnostic
marker for the infection in neonates at the time of initial assessment. In our study we used quantitative
assay for CRP estimation which less time consuming and effective in analyzing samples of neonates who
are already on antibiotics treatment.

Keywords: CRP, C-reactive proteins, Neonatal Sepsis, Transasia, Erba, Pathology, Blood Culture, HSS, Neonatal Septicemia, Dr Godbole Laboratory, Pune, Signs of neonatal sepsis.


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