Authors : Manish Raj Kulshrestha, Vandana Tiwari, Prateema Tripathi
DOI : 10.18231/j.ijcbr.2019.077
Volume : 6
Issue : 3
Year : 2019
Page No : 353-355
A well-known metabolite that is released under stress conditions, lactate can be easily assessed as a
diagnostic tool for patients under critical illness. The effect of elevated lactate level has been well studied
but due to the lack of a standard cut-off value of this metabolite it has not been decided to be used as a
biomarker for further care and hemodynamic management of patients suffering from Acute myocardial
infarction or any other cardiogenic shock/stress condition. The mechanism(s) associated with disturbed
lactate levels under hypothemic conditions ranges from various side effects of reduced temperatures to
the hemodynamic effects of hypothermia (i.e., reduced need of vasopressor agents). The present article is
focused on the estimation of plasma lactate level in AMI patients along with their cardiac Troponin-I levels
to study the correlation between the two and to look into the possibility of dual marker approach to deal
wit h complications associated with acute myocardial infarction. Serial measurement of serum lactate with
proper time management is recommended for clinically reliability in acute cardiac patients.
Keywords: Acute myocardial infarction, Serum lactate, Cardiac TroponinI.