Study of choroidal neovascularization and its outcome after anti-vegf treatment

Authors : Richa Gour

DOI : 10.18231/j.ijceo.2019.123

Volume : 5

Issue : 4

Year : 2019

Page No : 529-533

Aim: To evaluate the visual outcome and clinical response in CNVM patient after Anti-VEGF treatment.
Material and Methods: This prospective observational study was conducted on 38 diagnosed eye of
CNVM and its presence was confirmed by FFA. Complete ocular examination was conducted with respect
to CNVM. They were followed up post injection (inj.ranibizumab) at day 1,7,1 month and on PRN basis,
change in visual acuity and OCT findings was recorded.
Results: Mean age of study participants were 62.215.9. Majority (63.3%) of the patients were more than
60 years of age. Out of 30 patients 18 were males and 12 were females with M: F ratio 6:4. Difference
in visual acuity at pre and post treatment was significant with p value (<0> difference was found between pre and post treatment macular thickness on OCT (p value <0> Conclusion: Intravitreal ranibizumab injection was beneficial treatment for all type of CNVM administered
on PRN basis over 18 month of follow-up achieved stabilization of vision with significant improvement in
BCVA and decreased retinal thickness by OCT.

Keywords: Optical coherence tomography (OCT), Fundus fluorescence angiography (FFA), Prorenata (PRN).


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